ALNY

Alnylam Pharmaceuticals, Inc.
232.40 +2.47% 2026-10-28

Analysts 16 firms · 13 buy · 3 hold · target 354 +52% (253–455)

Last 90d 1 insider sale · 1 congress sale

52-week range
197.81 484.61
1-month-8.5%
3-month+13.1%
1-year-51.4%
3-year+43.5%
5-year+14.0%
vs 50-day-2.8%
vs 200-day-19.2%
Volatility48%
Beta0.43
$ vol/day$320M
ATH495.55
From ATH-53.1%
Next report2026-10-29
WhoEntryMove What they saidWhen
TRACKER - Analyst Ratings long 220.33 +5.5% Raymond James upgraded ALNY, Outperform to Strong Buy with a $420 target, on 3 August 2026. The price shown is where… Tue, 04 Aug
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

WhenPeople SizeValuePrice
23d sell 1 $398,855 223.18
5mo sched 1 $1,145,853 288.13
7mo sched 1 $1,274,343 317.95
8mo sell 3 $2,490,915 316.63
8mo sched 2 $1,942,481 316.63
8mo sell 3 $3,474,083 322.62
8mo sched 2 $2,181,904 322.62
8mo sched 1 $1,533,100 328.79
8mo sell 4 $4,155,382 325.92
8mo sched 1 $1,284,977 325.92
9mo sell 4 $5,579,779 365.83
9mo sched 1 $1,395,992 365.83
11mo sched 1 $5,483,990 461.11
11mo sched 1 $11,613,003 455.12
1.1y sell 4 $7,499,946 456.74
1.1y sched 1 $2,692,062 456.74
1.1y sched 1 $8,416,730 469.75
1.2y sched 1 $1,557,649 448.00
1.2y sell 4 $5,459,590 456.88
1.2y sched 2 $6,362,246 456.88
1.2y sched 1 $13,729,536 443.87
1.4y sched 1 $15,535,784 304.69
1.4y sched 1 $3,124,217 291.11
1.5y sell 1 $8,383 261.50
1.5y buy 1 $10,363 261.50
1.6y sched 2 $5,089,545 286.48
1.7y sell 3 $1,368,126 245.69
1.7y sched 2 $1,290,454 245.69
1.7y sell 5 $1,363,122 245.95
1.7y sell 2 $556,276 254.58
1.7y sched 2 $1,319,352 254.58
1.7y sched 1 $14,988,720 276.57
1.8y sched 1 $3,093,750 275.60
1.9y sched 1 $439,760 245.70
1.9y sell 4 $2,522,827 253.14
1.9y sched 1 $754,947 253.14
2.2y sched 1 $4,200,000 276.09
2.2y sched 1 $5,968,516 265.12
2.2y sched 1 $5,305,586 266.81
2.2y sched 1 $4,089,960 266.51
2.3y sched 1 $1,851,273 261.26
2.3y sched 1 $2,040,000 247.72
2.3y sell 5 $3,421,473 242.92
2.3y sched 1 $7,161,360 242.92
2.4y sched 1 $3,224,546 149.56
2.7y sched 1 $4,540,071 152.95
2.7y sell 5 $762,546 153.26
2.7y sell 4 $1,533,047 147.94
2.7y sell 1 $272,050 170.37
2.8y sched 1 $5,850,000 194.08
3.2y sell 4 $3,560,315 184.40
3.2y sell 1 $1,195,310 186.66
3.5y sell 5 $3,271,054 197.72
3.6y sell 1 $735,000 205.61
3.6y sell 1 $3,614,400 197.97
3.7y sell 1 $8,216,324 224.51
3.7y sell 2 $1,535,255 230.82
3.9y sell 1 $4,950,000 211.06
4.2y sell 1 $7,760,736 224.60
4.2y sell 1 $769,970 219.74
4.3y sell 1 $263,100 151.67
4.6y sell 1 $2,560,371 162.72
4.7y sell 1 $4,500,000 151.26
4.9y sell 1 $549,698 191.12
5.0y sell 1 $5,827,801 172.32
5.2y sell 1 $6,788,196 196.03
5.2y sell 1 $2,166,800 205.30
5.2y sell 2 $12,449,236 197.32
5.3y sell 1 $1,219,098 173.02
5.4y sell 1 $2,573,900 170.82
5.4y sell 1 $267,036 163.55
5.5y sell 1 $4,443,725 135.38
5.5y sell 1 $884,327 136.30
5.7y sell 1 $5,005,421 146.45
5.8y sell 1 $1,533,698 168.18
5.8y sell 2 $3,013,476 169.68
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

CBCory A Booker 1S 3mo JSJefferson Shreve 1S 1.5y JGJosh Gottheimer 4B4S 2.8y DGDaniel Goldman 1B1S 3.7y BCBarbara J Comstock 1B1S 8.7y RHRichard L. Hanna 2B2S 9.8y

6 members · 8 buys / 10 sells · $335K–$965K disclosed · latest filing Sep 9, 2026 · full tracker ›

WhenMemberSize AmountPrice then
3mo sell CB Cory A Booker $1K–$15K 221.20
1.5y sell JS Jefferson Shreve $15K–$50K 270.19
2.8y sell JG Josh Gottheimer $1K–$15K 180.96
2.8y buy JG Josh Gottheimer $1K–$15K 195.08
2.9y sell JG Josh Gottheimer $1K–$15K 170.92
3.7y buy DG Daniel Goldman $15K–$50K 199.70
3.7y sell DG Daniel Goldman $15K 226.40
4.1y buy JG Josh Gottheimer $1K–$15K 210.76
6.0y sell JG Josh Gottheimer $1K–$15K 135.51
6.6y buy JG Josh Gottheimer $1K–$15K 112.14
8.0y sell JG Josh Gottheimer $1K–$15K 78.59
8.4y buy JG Josh Gottheimer $1K–$15K 100.65
8.7y sell BC Barbara J Comstock $15K–$50K 126.58
9.1y buy BC Barbara J Comstock $15K–$50K 124.20
9.8y sell RH Richard L. Hanna $1K–$15K 37.44
9.8y buy RH Richard L. Hanna $50K–$100K 37.44
9.9y sell RH Richard L. Hanna $100K–$250K 43.91
10.0y buy RH Richard L. Hanna $100K–$250K 36.17

Next report 2026-10-29 (Thursday, before open, in 0 days) · EPS estimate 2.25. It has finished the next session higher 50% of the time, average move 5.3%.

Day-after move, last 12 reports, oldest left.

ReportedEst.Actual SurpriseGapDay 1Day 5
2026-07-30 miss 2.14 1.84 -14.2% -21.5% -28.3% -24.6%
2026-04-30 beat 1.47 1.99 +35.3% +2.1% +2.8% -1.8%
2026-02-12 miss 1.50 1.25 -16.5% -2.4% -4.3% +4.3%
2025-10-30 beat 1.75 2.90 +66.1% -6.6% -6.7% -8.5%
2025-07-31 beat 0.15 0.32 +119.6% +3.0% +15.4% +28.0%
2025-05-01 beat -0.37 -0.01 +97.3% -2.3% -3.1% -1.9%
2025-02-13 beat -0.14 0.06 +142.5% -2.8% -0.4% -5.8%
2024-10-31 miss -0.39 -0.50 -26.7% -2.2% -5.3% -3.3%
2024-08-01 beat -0.69 0.56 +181.1% +5.3% +13.1% +13.9%
2024-05-02 beat -0.63 -0.16 +74.5% +0.6% +0.2% +0.9%
2024-02-15 miss -0.77 -0.77 -0.2% -8.6% -10.2% -4.0%
2023-11-02 beat -0.96 1.74 +281.9% +3.4% +2.9% +4.8%
2023-08-03 miss -1.34 -1.62 -21.2% -2.6% +1.7% -1.1%
2023-05-04 beat -1.43 -1.06 +25.7% +1.1% +3.0% +3.3%
2023-02-23 beat -1.48 -1.39 +6.3% -1.5% -2.4% -3.3%
2022-10-27 miss -1.38 -1.58 -14.6% -1.8% -3.5% +7.3%
2022-07-28 miss -1.36 -2.03 -49.4% -3.5% +1.1% +57.8%
2022-04-28 miss -1.46 -1.49 -2.1% -2.9% -7.6% -11.7%
2022-02-10 miss -1.26 -1.69 -34.4% -2.1% -0.4% -1.0%
2021-10-28 miss -1.24 -1.51 -21.4% -11.6% -15.2% -2.9%
2021-08-03 miss -1.28 -1.30 -1.2% +0.7% +0.5% +16.7%
2021-04-29 miss -1.40 -1.64 -17.1% +1.0% -2.7% -8.0%
2021-02-11 miss -1.38 -1.60 -15.9% +1.7% +0.7% -5.5%
2020-11-05 miss -1.34 -1.58 -18.0% +2.9% -1.2% -5.1%
2020-08-06 miss -1.40 -1.67 -19.4% -1.2% -4.2% -8.6%
2020-05-06 miss -1.51 -1.52 -0.9% +0.0% +2.9% -1.3%
2020-02-06 miss -1.92 -1.98 -3.1% -4.9% +0.3% +7.0%
2019-10-31 beat -1.83 -1.50 +18.1% -2.2% -0.6% +4.9%
2019-08-06 beat -1.85 -1.83 +1.2% -2.0% +4.2% +12.0%
2019-05-01 beat -1.80 -1.42 +21.1% +2.9% -7.1% -21.5%
2019-02-07 beat -1.93 -1.82 +5.7% +1.9% -3.8% +3.4%
2018-11-07 beat -1.79 -1.56 +12.9% -7.8% -11.9% -24.6%
2018-08-02 miss -1.71 -1.83 -6.9% +3.7% +0.8% -0.3%
2018-05-03 beat -1.51 -1.41 +6.4% +0.8% +4.6% +14.3%
2018-02-08 miss -1.36 -1.48 -8.7% +0.8% -4.7% -0.3%
2017-11-07 miss -1.23 -1.34 -9.3% +1.3% +2.2% -2.7%
2017-08-09 miss -1.17 -1.34 -14.7% -2.9% -5.7% -0.3%
2017-05-05 miss -1.24 -1.25 -0.5% -2.6% +0.4% +3.5%
2017-02-08 miss -1.31 -1.32 -0.9% +12.7% +10.7% +15.7%
2016-11-02 miss -1.16 -1.21 -4.0% +0.8% -12.6% +27.3%
2016-08-04 beat -1.27 -1.05 +17.4% +1.5% +10.4% +4.3%
2016-05-02 miss -1.08 -1.21 -11.9% -2.9% -11.6% -16.5%
2016-02-11 miss -0.92 -1.07 -16.0% -8.0% +4.5% +10.0%
2015-11-09 miss -0.90 -0.91 -1.5% -1.6% +7.2% -0.2%
2015-08-06 miss -0.73 -0.85 -16.8% -8.2% -11.4% -11.8%
2015-05-07 miss -0.60 -0.62 -2.7% -1.0% +5.8% +12.4%
2015-02-12 beat -0.57 -0.28 +50.9% +2.3% +1.8% +10.9%
2014-11-05 beat -0.64 -0.58 +9.0% +1.2% +5.6% +12.9%
2014-08-07 miss -0.55 -0.63 -15.0% -3.0% +3.6% +19.9%
2014-05-08 beat -0.54 -0.39 +27.4% -5.1% +8.1% +14.0%
2014-02-13 miss -0.43 -0.51 -17.5% -0.1% -3.5% +7.5%
2013-11-06 miss -0.39 -0.48 -22.0% -0.1% -7.4% -7.6%
2013-08-08 beat -0.33 -0.29 +12.5% +1.9% +1.8% +1.9%
2013-05-06 beat -0.31 -0.15 +51.8% +2.6% +3.0% +18.1%
2013-02-07 miss -0.95 -1.20 -26.3% +2.6% +4.1% +1.0%
2012-11-05 miss -0.32 -0.38 -20.2% +0.0% -3.1% +1.3%
2012-08-06 miss -0.21 -0.25 -19.8% -5.7% -1.4% -7.8%
2012-05-03 beat -0.34 -0.25 +27.5% +1.0% -5.0% +3.9%
2012-02-09 miss -0.33 -0.33 -1.3% -3.4% -6.9% -6.5%
2011-11-01 beat -0.35 -0.31 +11.9% +2.8% +0.6% -5.0%

16 firms covering, 31 actions in the last 180 days (ratings, reiterations and target changes) · average price target 354 from 16 firms, range 253–455.

DateFirmActionRating TargetFrom
2026-10-14 Citigroup main Buy 320 340
2026-10-14 Wells Fargo main Equal-Weight 253 256
2026-10-08 RBC Capital main Outperform 345 350
2026-09-30 JP Morgan main Overweight 369 375
2026-09-21 HC Wainwright & Co. reit Buy 455 —
2026-09-08 Jefferies main Hold 260 230
2026-09-02 HC Wainwright & Co. reit Buy 455 —
2026-08-19 BMO Capital init Outperform 318 —
2026-08-14 Wells Fargo main Equal-Weight 256 316
2026-08-04 Truist Securities main Buy 315 410
2026-08-04 HC Wainwright & Co. main Buy 455 485
2026-08-03 Raymond James up Strong Buy 420 —
2026-08-03 Citigroup main Buy 340 380
2026-08-03 Barclays main Overweight 450 527
2026-07-31 JP Morgan main Overweight 375 400
2026-07-31 RBC Capital main Outperform 350 445
2026-07-31 Morgan Stanley main Equal-Weight 300 400
2026-07-31 Oppenheimer main Outperform 350 500
2026-07-31 Wells Fargo main Equal-Weight 316 377
2026-07-31 Stifel main Buy 318 444
2026-07-31 Chardan Capital main Buy 425 —
2026-07-30 Needham main Buy 357 510
2026-07-22 JP Morgan main Overweight 400 420
2026-07-14 B of A Securities main Buy 410 460
2026-07-13 Truist Securities main Buy 410 505
2026-07-13 HC Wainwright & Co. main Buy 485 470
2026-07-10 Morgan Stanley main Equal-Weight 400 370
2026-06-29 HC Wainwright & Co. main Buy 470 510
2026-06-04 HC Wainwright & Co. reit Buy 510 —
2026-05-19 Citigroup init Buy 380 —
2026-05-05 HC Wainwright & Co. reit Buy 510 —
Model view — historical tendencies for the days ahead, not a forecast
Next 1 day
+0.1%
Next 1 week
+0.7%
Next 1 month
+1.3%
Seasonality
Bullish window historically
Next 30 days (to Nov 28): +5.5% median, 67% of the last 21 years finished up.
20-year seasonality chart →
Mean reversion
Overbought — RSI(2) at 86
RSI(2) under 15 is oversold (this name has historically bounced); over 85 is overbought. Its dip-buy edge in history is -0.01%/day.
Mean-reversion stats →
1-month breakdown — Market · β 0.43 +1.1% · Seasonal tilt +0.2%
$30.0B market cap (#373 US) $320M/day volume 48% volatility -51% 1-year -53% from ATH
52-week range · 12% of the way up · -52% from the high
$197.81$484.61

Not investment advice.