SEPN

Septerna, Inc.
45.23 +2.21% 2026-10-29

Last 90d 6 insider sales

52-week range
17.55 51.10
1-month+15.6%
3-month+31.3%
1-year+102.6%
vs 50-day+16.3%
vs 200-day+41.4%
Volatility67%
Beta0.97
$ vol/day$14M
ATH51.10
From ATH-11.5%
Next report2026-11-09
WhoEntryMove What they saidWhen
TRACKER - Insider Trades long 5.85 +673.2% Third Rock Ventures GP V, LP has been buying SEPN. The buy: Third Rock Ventures GP V, LP, a 10%+ owner, bought… Mon, 24 Feb 2025
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

WhenPeople SizeValuePrice
11d sched 1 $149,644 36.92
2mo sched 1 $126,078 37.33
3mo sell 1 $63,452,500 45.07
3mo sched 1 $7,399,858 45.07
3mo sched 1 $1,100,000 47.03
3mo sched 1 $114,920 39.55
3mo sched 1 $135,974 32.41
4mo sched 1 $114,528 34.05
4mo sched 1 $76,622 33.72
4mo sched 1 $532,590 36.80
4mo sched 1 $219,250 35.84
5mo sched 1 $171,665 30.20
5mo sched 1 $354,648 30.31
6mo sched 1 $97,354 25.70
8mo sched 1 $1,979,971 28.26
8mo sched 1 $115,856 26.45
12mo sell 1 $63,228 19.00
1.6y buy 1 $92,301 6.15
1.7y buy 1 $515,898 5.97
1.7y buy 2 $153,867 5.83
1.7y buy 1 $113,166 5.67
1.7y buy 1 $6,167,378 6.11
1.7y buy 1 $172,365 5.93
2.0y buy 1 $75,060,000 19.71
2.0y buy 1 $11,700,000 20.76

Next report 2026-11-09 (Monday, after close, in 10 days) · EPS estimate -0.40. It has finished the next session higher 38% of the time, average move 5.6%.

Day-after move, last 8 reports, oldest left.

ReportedEst.Actual SurpriseGapDay 1Day 5
2026-08-10 beat -0.49 -0.29 +41.2% +1.9% +22.9% +12.7%
2026-05-11 beat -0.44 -0.19 +56.9% +3.8% +5.4% +12.5%
2026-03-09 miss -0.22 -0.24 -8.5% +1.2% -3.6% -13.4%
2025-11-10 miss 0.79 -0.10 -112.3% +1.5% -2.2% +16.9%
2025-08-11 miss 0.93 -0.56 -160.4% -4.3% -2.5% -4.9%
2025-05-15 miss -0.38 -0.49 -29.9% +4.4% -2.8% -9.2%
2025-03-27 miss -0.42 -0.64 -52.4% +1.3% +2.4% -5.5%
2024-11-20 miss -0.94 -8.40 -793.6% +1.2% -3.2% +12.4%
Model view — historical tendencies for the days ahead, not a forecast
Next 1 day
-0.1%
Next 1 week
+1.7%
Next 1 month
+2.8%
Seasonality
Not enough history
20-year seasonality chart →
Mean reversion
Deeply overbought — RSI(2) at 98
RSI(2) under 15 is oversold (this name has historically bounced); over 85 is overbought. Its dip-buy edge in history is -0.26%/day.
Mean-reversion stats →
1-month breakdown — Market · β 0.97 +2.8%
$14M/day volume 67% volatility +103% 1-year -12% from ATH
52-week range · 83% of the way up · -12% from the high
$17.55$51.10

Not investment advice.