SY
SYRE
Spyre Therapeutics, Inc.
99.75
+0.71%
2026-10-28
Last 90d 4 insider sales
52-week range
21.15
110.18
1-month+17.7%
3-month-1.7%
1-year+306.0%
3-year+703.8%
5-year-47.2%
vs 50-day+10.2%
vs 200-day+37.5%
Volatility66%
Beta1.75
$ vol/day$120M
ATH318.75
From ATH-68.7%
Next report2026-11-03
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2026AprJulOct
bought sold · bigger dot, bigger trade · follows the chart’s range
| When | People | Size | Value | Price | |
|---|---|---|---|---|---|
| 28d | sched | 3 | $6,275,837 | 92.88 | |
| 2mo | sched | 3 | $6,073,760 | 86.84 | |
| 3mo | sched | 1 | $2,404,190 | 105.16 | |
| 3mo | sched | 2 | $2,149,476 | 104.51 | |
| 4mo | sched | 3 | $2,704,281 | 87.43 | |
| 4mo | sell | 1 | $1,307,000 | 88.48 | |
| 4mo | sell | 1 | $399,658,667 | 98.69 | |
| 4mo | sched | 1 | $2,000,000 | 98.69 | |
| 5mo | sched | 3 | $2,214,398 | 72.97 | |
| 6mo | sched | 1 | $5,952,050 | 74.16 | |
| 6mo | sched | 3 | $7,563,333 | 72.59 | |
| 7mo | sched | 3 | $1,507,888 | 48.32 | |
| 8mo | sched | 2 | $734,486 | 40.91 | |
| 9mo | sched | 1 | $492,045 | 32.50 | |
| 10mo | sched | 1 | $460,134 | 29.91 | |
| 11mo | sched | 1 | $435,356 | 30.38 | |
| 12mo | sched | 1 | $1,049,778 | 22.77 | |
| 1.2y | sell | 1 | $299,639 | 16.88 | |
| 2.0y | sched | 1 | $246,292 | 36.31 | |
| 2.0y | sched | 1 | $10,929 | 35.19 | |
| 2.2y | sell | 1 | $522,018 | 28.29 |
Next report 2026-11-03 (Tuesday, after close, in 5 days) · EPS estimate -0.84. It has finished the next session higher 52% of the time, average move 3.8%.
Day-after move, last 12 reports, oldest left.
| Reported | Est. | Actual | Surprise | Gap | Day 1 | Day 5 | |
|---|---|---|---|---|---|---|---|
| 2026-08-04 | beat | -0.75 | -0.36 | +51.8% | +0.0% | -0.6% | -0.8% |
| 2026-05-05 | miss | -0.65 | -0.74 | -13.1% | +2.2% | +2.7% | +8.5% |
| 2026-02-19 | beat | -0.80 | -0.74 | +7.2% | +0.0% | +14.3% | +13.8% |
| 2025-11-04 | beat | -0.74 | -0.15 | +79.7% | +1.7% | -0.6% | +2.0% |
| 2025-08-05 | beat | -0.71 | -0.49 | +31.1% | +0.1% | -5.4% | +3.1% |
| 2025-05-08 | beat | -0.84 | -0.60 | +28.6% | +5.3% | +9.6% | +18.0% |
| 2025-02-27 | beat | -0.94 | -0.81 | +14.2% | +1.7% | +7.2% | +6.1% |
| 2024-11-07 | miss | -0.86 | -1.36 | -57.8% | -4.8% | +5.0% | -22.5% |
| 2024-08-07 | beat | -0.91 | -0.86 | +5.5% | +3.6% | +2.9% | +8.1% |
| 2024-05-09 | miss | -1.08 | -1.20 | -11.1% | +9.8% | +4.9% | +7.4% |
| 2024-02-29 | miss | -0.83 | -4.05 | -389.1% | +10.0% | +9.0% | +38.2% |
| 2023-11-09 | miss | -0.84 | -9.34 | -1005.3% | -2.5% | +0.2% | +8.2% |
| 2023-08-11 | miss | -3.50 | -56.75 | -1521.4% | -9.0% | -4.8% | -6.7% |
| 2023-05-11 | miss | -4.37 | -5.00 | -14.3% | -1.8% | -3.7% | -10.4% |
| 2023-03-02 | beat | -5.06 | -4.50 | +11.1% | +1.0% | -1.3% | +5.3% |
| 2022-11-03 | beat | -5.87 | -4.75 | +19.1% | -1.6% | -6.6% | +26.2% |
| 2022-08-04 | beat | -7.75 | -6.75 | +12.9% | +5.1% | +6.4% | +28.2% |
| 2022-05-05 | miss | -8.59 | -9.25 | -7.7% | -3.8% | +1.3% | -16.0% |
| 2022-03-08 | miss | -7.63 | -7.75 | -1.5% | -7.7% | +3.9% | -19.7% |
| 2021-11-04 | miss | -7.34 | -7.75 | -5.6% | -3.6% | -1.0% | -5.8% |
| 2021-08-05 | beat | -4.30 | -2.50 | +41.9% | +0.8% | +3.2% | -5.8% |
| 2021-05-10 | miss | -3.49 | -7.00 | -100.5% | -0.3% | -2.8% | +3.2% |
| 2021-03-18 | miss | -8.28 | -8.50 | -2.6% | -0.9% | -3.6% | +4.8% |
| 2020-11-05 | beat | -9.97 | -7.25 | +27.3% | +0.1% | +8.1% | +17.7% |
| 2020-08-10 | beat | -10.76 | -10.00 | +7.1% | -0.1% | -3.0% | -0.9% |
| 2020-05-07 | beat | -16.41 | -14.25 | +13.2% | +4.0% | +5.5% | -10.1% |
| 2020-02-24 | beat | -16.61 | -16.25 | +2.1% | -4.7% | -5.7% | -12.6% |
| 2019-11-06 | miss | -13.31 | -16.50 | -24.0% | -0.9% | -2.1% | -3.9% |
| 2019-08-06 | miss | -12.08 | -13.75 | -13.8% | -1.4% | -2.8% | -2.0% |
| 2019-05-07 | miss | -13.80 | -14.75 | -6.8% | -1.0% | -3.1% | -2.7% |
| 2019-03-07 | miss | -9.15 | -15.50 | -69.4% | -0.5% | -2.4% | -2.4% |
| 2018-11-08 | miss | -10.80 | -13.50 | -25.0% | -3.4% | +4.8% | -11.1% |
| 2018-08-09 | miss | -8.62 | -11.50 | -33.3% | -1.5% | +5.9% | +1.9% |
| 2018-05-08 | miss | -11.51 | -12.25 | -6.4% | -0.2% | +1.0% | +7.7% |
| 2018-03-13 | beat | -13.22 | -9.75 | +26.2% | -1.2% | +0.2% | +22.9% |
| 2017-11-07 | beat | -13.77 | -12.00 | +12.9% | +0.4% | -3.7% | -4.1% |
| 2017-08-09 | beat | -12.00 | -11.75 | +2.1% | +10.1% | +0.3% | -2.3% |
| 2017-05-09 | miss | -11.70 | -11.75 | -0.5% | -0.9% | -3.0% | -0.6% |
| 2017-03-23 | beat | -12.75 | -8.25 | +35.3% | +0.0% | +0.7% | +1.8% |
| 2016-11-09 | beat | -13.59 | -11.75 | +13.6% | -4.2% | -1.8% | +1.0% |
| 2016-08-09 | miss | -10.50 | -11.50 | -9.5% | -0.2% | +3.0% | +13.0% |
| 2016-05-19 | beat | -12.16 | -8.80 | +27.6% | -5.3% | -0.7% | +0.5% |
Model view — historical tendencies for the days ahead, not a forecast
Next 1 day
-0.6%
Next 1 week
+2.7%
Next 1 month
+4.5%
Seasonality
Bullish window historically
Next 30 days (to Nov 28): +6.3% median,
67% of the last 9 years finished up.
20-year seasonality chart →
Mean reversion
Deeply overbought — RSI(2) at 94
RSI(2) under 15 is oversold (this name has historically bounced); over 85 is overbought.
Its dip-buy edge in history is -0.22%/day.
Mean-reversion stats →
1-month breakdown —
Market · β 1.75 +4.6% · Seasonal tilt (9y) -0.1%
$120M/day volume
66% volatility
+306% 1-year
-69% from ATH
52-week range · 88% of the way up · -10% from the high
$21.15$110.18
Not investment advice.
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