VRTX

Vertex Pharmaceuticals Incorporated
540.00 +1.95% 2026-10-29

Analysts 10 firms · 8 buy · 1 hold · 1 sell · target 550 +2% (350–617)

Last 90d 1 congress sale

52-week range
403.16 560.25
1-month+3.3%
3-month+13.2%
1-year+27.8%
3-year+46.2%
5-year+188.6%
vs 50-day+3.3%
vs 200-day+12.8%
Volatility29%
Beta0.49
$ vol/day$661M
ATH560.25
From ATH-3.6%
Next report2026-11-02
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2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

WhenPeople SizeValuePrice
4mo sched 2 $1,587,264 523.22
4mo sched 1 $416,244 521.16
4mo sched 1 $287,570 495.31
4mo sched 1 $471,413 467.29
4mo sched 1 $1,827,900 455.93
5mo sched 1 $785,250 445.20
5mo sched 1 $364,245 424.51
5mo sched 1 $888,300 429.45
5mo sched 2 $628,935 438.74
6mo sched 1 $3,144,600 452.02
6mo sched 2 $603,968 423.11
7mo sched 1 $439,288 437.17
7mo sched 1 $1,050,263 445.22
7mo sched 1 $1,122,089 464.98
8mo sched 1 $1,312,340 477.87
8mo sched 1 $1,158,306 455.34
8mo sched 1 $442,396 475.56
8mo sched 2 $20,857,497 477.84
8mo sched 1 $172,560 491.21
8mo sched 7 $4,613,094 479.11
8mo sched 1 $27,479,583 481.34
8mo sched 5 $6,471,647 467.62
8mo sched 3 $1,375,997 472.09
9mo sched 5 $3,471,182 464.50
10mo sched 1 $2,137,455 469.36
10mo sched 1 $4,394,252 475.49
11mo sched 4 $37,215,095 458.23
11mo sched 1 $1,086,450 426.73
11mo sched 1 $32,292,320 436.12
1.1y sched 1 $280,522 407.48
1.2y sched 1 $102,860 391.96
1.2y buy 2 $5,844,183 381.38
1.4y sched 1 $22,084 438.39
1.5y sched 1 $202,344 501.81
1.6y sched 1 $1,647,810 510.60
1.6y sched 3 $4,885,468 489.87
1.7y sched 1 $1,970,118 485.70
1.7y sched 1 $1,583,190 489.54
1.7y sched 3 $2,122,141 479.50
1.7y sched 4 $1,853,100 479.61
1.7y sched 1 $533,280 483.27
1.7y sched 3 $1,170,414 467.01
1.7y sched 4 $3,157,330 450.83
1.9y sched 1 $7,178 455.52
2.0y sched 1 $1,554,810 494.64
2.0y sched 1 $7,826,970 498.53
2.1y sched 1 $461,198 457.19
2.2y sched 2 $2,211,216 476.49
2.2y sched 1 $602,447 464.91
2.2y sched 1 $1,086,990 468.24
2.2y sched 1 $2,689,860 499.82
2.2y sched 1 $7,677,010 503.25
2.3y sched 1 $1,113,689 497.35
2.3y sched 1 $7,555,394 489.12
2.3y sched 1 $1,111,135 492.58
2.3y sched 1 $1,075,522 472.49
2.4y sched 2 $4,573,504 476.98
2.4y sched 2 $2,495,500 479.31
2.4y sched 1 $2,033,158 462.56
2.4y sched 1 $1,015,877 450.19
2.4y sched 1 $1,478,068 439.41
2.4y sched 1 $715,205 444.38
2.4y sched 1 $3,168,704 453.54
2.4y sched 1 $6,795,294 445.65
2.5y sched 3 $66,794 443.23
2.5y sched 1 $188,178 401.63
2.6y sched 1 $100,560 411.61
2.7y sched 6 $6,128,803 433.76
2.7y sched 5 $4,790,042 431.78
2.7y sched 5 $6,034,549 419.40
2.7y sched 1 $3,776,528 424.00
2.7y sched 1 $1,423,104 417.36
2.7y sched 7 $6,301,465 416.10
2.8y sched 1 $2,785,977 421.54
2.8y sched 1 $1,215,000 414.91
2.9y sched 1 $6,973,945 399.38
2.9y sched 3 $10,790,302 406.06
2.9y sched 1 $1,049,640 354.76
3.0y sched 2 $19,976 347.13
3.0y sched 1 $2,151,633 346.98
3.0y sched 1 $1,921,569 359.31
3.0y sched 1 $4,331,250 376.27
3.0y sched 1 $2,011,304 372.28
3.0y sched 2 $2,200,361 365.70
3.0y sched 1 $4,847,788 371.16
3.1y sched 1 $87,120 362.20
3.1y sched 1 $1,951,177 353.50
3.1y sched 1 $211,524 344.82
3.1y sched 1 $1,983,501 353.10
3.1y sched 1 $1,992,882 346.15
3.2y sched 1 $887,500 348.12
3.2y sched 3 $8,999,142 349.97
3.2y sched 2 $105,381 348.67
3.3y sched 2 $6,792,399 356.41
3.4y sched 1 $3,002,447 346.35
3.4y sched 2 $122,363 322.29
3.5y sched 2 $1,845,100 344.58
3.5y sched 2 $5,379,248 347.07
3.5y sched 1 $202,004 347.28
3.5y sched 1 $1,124,726 342.74
3.5y sched 2 $9,431,586 332.77
3.6y sched 1 $164,854 322.89
3.6y sched 1 $539,912 311.38
3.6y sched 1 $592,786 301.54
3.6y sched 1 $825,423 298.41
3.6y sell 1 $1,388,054 293.13
3.7y sell 4 $3,114,434 288.58
3.7y sell 1 $706,679 289.12
3.7y sell 3 $2,022,273 293.33
3.7y sell 4 $4,572,757 294.94
3.7y sell 4 $3,011,109 298.18
3.7y sell 1 $399,022 298.10
3.7y sell 2 $424,462 308.41
3.7y sell 2 $1,325,583 322.59
3.8y sell 2 $5,679,674 321.62
3.8y sell 1 $1,915,044 313.66
3.8y sell 1 $1,386,099 307.03
4.0y sell 1 $10,493 306.94
4.0y sell 1 $394,859 308.88
4.0y sell 1 $100,045 309.35
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

DTDavid J. Taylor 1B2S 2mo AAAlan Armstrong 1B 7mo LMLisa McClain 1B2S 1.4y JSJefferson Shreve 2B1S 1.5y BDByron Donalds 1S 1.6y JLJulia Letlow 1B 2.0y TTThomas H Tuberville 1B1S 2.5y GSGreg Stanton 1S 3.0y WKWilliam R. Keating 1B 4.6y PMPeter Meijer 1S 5.8y DPDean Phillips 1B 5.9y JGJosh Gottheimer 2B4S 7.1y DSDonna Shalala 1B1S 7.4y GCGilbert Cisneros 3S 7.7y +3 more

17 members · 14 buys / 22 sells · $107K–$730K disclosed · latest filing Sep 5, 2026 · full tracker ›

WhenMemberSize AmountPrice then
2mo sell DT David J. Taylor $1K–$15K 547.29
7mo buy AA Alan Armstrong $1K–$15K 433.07
9mo sell DT David J. Taylor $1K–$15K 475.68
1.2y buy DT David J. Taylor $1K–$15K 375.63
1.4y sell LM Lisa McClain $1K–$15K 452.44
1.4y sell LM Lisa McClain $1K–$15K 451.52
1.5y sell JS Jefferson Shreve $15K–$50K 439.37
1.6y sell BD Byron Donalds $1K–$15K 510.18
1.6y buy JS Jefferson Shreve $15K–$50K 502.92
1.7y buy JS Jefferson Shreve $15K–$50K 481.65
1.9y buy LM Lisa McClain $1K–$15K 468.29
2.0y buy JL Julia Letlow $1K–$15K 470.05
2.5y sell TT Thomas H Tuberville $1K–$15K 401.08
3.0y sell GS Greg Stanton $1K–$15K 369.38
4.1y buy TT Thomas H Tuberville $1K–$15K 298.63
4.6y buy WK William R. Keating $1K–$15K 257.98
5.8y sell PM Peter Meijer $1K–$15K 230.04
5.9y buy DP Dean Phillips $1K–$15K 236.72
7.1y sell JG Josh Gottheimer $1K–$15K 176.14
7.4y sell DS Donna Shalala $1K–$15K 181.02
7.5y buy DS Donna Shalala $1K–$15K 168.16
7.6y sell JG Josh Gottheimer $1K–$15K 185.12
7.7y sell GC Gilbert Cisneros $15K–$50K 189.81
7.7y sell GC Gilbert Cisneros $15K–$50K 188.92
7.7y sell JR John F Reed $1K–$15K 187.98
7.8y sell GC Gilbert Cisneros $1K–$15K 190.91
8.4y sell JG Josh Gottheimer $1K–$15K 152.05
8.5y sell JG Josh Gottheimer $1K–$15K 152.48
8.6y sell JR John F Reed $1K–$15K 176.26
9.3y buy JG Josh Gottheimer $1K–$15K 159.69
9.6y buy JG Josh Gottheimer $1K–$15K 113.80
10.0y buy TM Thomas MacArthur $1K–$15K 78.00
10.0y buy TM Thomas MacArthur $1K–$15K 77.88
10.1y sell KC K. Michael Conaway $1K–$15K 97.86
10.7y sell TM Thomas MacArthur $1K–$15K 90.98
11.5y sell JR John F Reed $1K–$15K 125.52

Next report 2026-11-02 (Monday, after close, in 3 days) · EPS estimate 4.75. It has finished the next session higher 47% of the time, average move 3.4%.

Day-after move, last 12 reports, oldest left.

ReportedEst.Actual SurpriseGapDay 1Day 5
2026-08-03 miss 4.75 4.73 -0.3% +0.1% +1.7% +12.5%
2026-05-04 beat 4.31 4.47 +3.8% +0.5% -1.3% +4.3%
2026-02-12 miss 5.15 5.03 -2.3% +1.4% +5.7% +3.4%
2025-11-03 beat 4.58 4.80 +4.9% -1.7% -1.0% +0.8%
2025-08-04 beat 4.25 4.52 +6.3% -13.6% -20.6% -17.9%
2025-05-05 miss 4.29 4.06 -5.4% -6.9% -10.0% -13.6%
2025-02-10 miss 4.02 3.98 -1.0% -2.2% -3.1% +0.4%
2024-11-04 beat 4.13 4.38 +6.0% +2.2% +5.7% +3.6%
2024-08-01 miss -11.75 -12.83 -9.2% -2.8% -2.2% -7.4%
2024-05-06 beat 4.06 4.76 +17.3% +1.0% +1.9% +6.5%
2024-02-05 beat 4.09 4.20 +2.8% +0.0% -3.0% -3.0%
2023-11-06 beat 3.97 4.08 +2.7% -2.2% -1.9% -4.1%
2023-08-01 beat 3.88 3.89 +0.1% +0.6% +3.1% -0.8%
2023-05-01 beat 3.00 3.05 +1.6% +0.0% +0.3% +0.0%
2023-02-07 beat 3.51 3.76 +7.0% -1.8% -4.9% -3.2%
2022-10-27 beat 3.64 4.01 +10.1% +4.9% +9.0% +7.3%
2022-08-04 beat 3.50 3.60 +2.8% -0.6% +4.8% +7.2%
2022-05-05 miss 3.54 3.52 -0.4% -3.8% -4.7% -7.4%
2022-01-26 beat 3.29 3.37 +2.5% +1.1% +0.7% +7.6%
2021-11-02 beat 3.07 3.56 +15.8% +3.4% +4.2% +3.6%
2021-07-29 beat 2.38 3.11 +30.7% +0.6% +0.6% +0.1%
2021-04-29 beat 2.69 2.98 +10.8% +0.7% +3.0% +1.5%
2021-02-01 miss 2.55 2.51 -1.6% -2.6% -6.2% -7.7%
2020-10-29 beat 2.33 2.64 +13.3% -0.5% +0.7% +6.4%
2020-07-30 beat 2.08 2.61 +25.2% -0.2% -2.6% -2.3%
2020-04-29 beat 1.85 2.56 +38.6% +2.7% +0.1% +7.6%
2020-01-30 beat 1.22 1.70 +39.9% +3.6% -1.4% +4.2%
2019-10-30 beat 1.16 1.23 +5.7% -1.1% -1.9% -1.7%
2019-07-31 beat 1.07 1.26 +17.3% +4.1% +7.6% +9.8%
2019-04-30 beat 1.01 1.14 +13.1% -0.1% +2.1% +0.0%
2019-02-05 beat 1.06 1.30 +22.2% +3.2% -2.5% -0.9%
2018-10-24 beat 1.01 1.09 +8.0% -3.7% +1.5% +7.4%
2018-07-25 beat 0.75 0.94 +25.9% +1.0% -0.5% +0.6%
2018-04-26 beat 0.63 0.76 +20.9% -0.8% -1.7% -5.9%
2018-01-31 beat 0.54 0.61 +13.6% +4.3% +3.7% -9.2%
2017-10-25 beat 0.37 0.53 +44.0% -1.3% -2.1% -1.3%
2017-07-26 beat 0.36 0.39 +8.1% -1.6% -4.4% -5.7%
2017-04-27 beat 1.05 1.33 +26.9% +1.8% +0.7% -2.2%
2017-01-25 beat 0.29 0.35 +21.4% +0.7% +0.2% +1.8%
2016-10-25 miss 0.19 0.16 -14.8% +4.1% +0.0% -0.9%
2016-07-27 beat 0.20 0.24 +17.2% -0.7% +0.2% +4.4%
2016-04-27 miss 0.28 0.09 -67.7% -3.9% +2.7% -0.6%
2016-01-27 beat 0.16 0.17 +8.5% -1.6% +0.3% -0.8%
2015-10-28 beat -0.27 -0.13 +52.3% +5.4% +5.1% +1.5%
2015-07-29 beat -0.58 -0.54 +7.6% +0.4% +7.8% +11.0%
2015-04-29 miss -0.57 -0.62 -9.2% +0.3% -0.4% +1.0%
2015-01-28 miss -0.46 -0.55 -19.2% -7.3% -5.9% -8.0%
2014-10-28 beat -0.43 -0.37 +14.8% -0.2% -3.6% -2.2%
2014-07-29 miss -0.54 -0.61 -13.5% -2.2% -3.7% -9.2%
2014-05-01 miss -0.64 -0.65 -2.2% +0.6% -3.7% -5.7%
2014-01-29 miss -0.49 -1.21 -145.4% +2.5% +4.2% -0.8%
2013-10-29 miss -0.16 -0.32 -102.7% -2.2% -2.2% -16.0%
2013-07-29 beat -0.06 -0.03 +50.5% +2.3% +2.8% -2.9%
2013-04-30 beat -0.06 0.03 +147.5% +0.7% +0.0% -1.8%
2013-01-29 miss 0.10 0.04 -58.3% +0.3% -3.8% -1.1%
2012-11-01 miss 0.34 0.13 -61.9% -9.8% -10.8% -10.8%
2012-07-30 miss 0.68 0.46 -32.6% -0.4% -2.9% +3.1%
2012-04-26 miss 0.59 0.55 -6.3% -1.7% +2.9% -0.3%
2012-02-02 miss 0.85 0.72 -15.8% -2.2% -4.2% -5.9%
2011-10-27 beat 0.26 0.56 +110.8% +0.4% -2.3% -14.0%

10 firms covering, 16 actions in the last 180 days (ratings, reiterations and target changes) · average price target 550 from 10 firms, range 350–617.

DateFirmActionRating TargetFrom
2026-10-08 RBC Capital main Outperform 576 570
2026-09-28 UBS main Buy 615 585
2026-08-05 Truist Securities main Buy 565 560
2026-08-05 Barclays main Overweight 617 615
2026-08-04 TD Cowen main Buy 550 525
2026-08-04 Cantor Fitzgerald main Overweight 595 590
2026-08-04 Canaccord Genuity main Hold 442 436
2026-07-13 UBS main Buy 585 545
2026-07-13 Truist Securities main Buy 560 542
2026-07-07 RBC Capital main Outperform 570 543
2026-07-07 Baird main Underperform 350 330
2026-05-06 Barclays main Overweight 615 607
2026-05-05 Canaccord Genuity main Hold 436 437
2026-05-05 Morgan Stanley main Overweight 616 612
2026-05-05 Bernstein main Outperform 572 577
2026-05-05 RBC Capital main Outperform 543 541
Model view — historical tendencies for the days ahead, not a forecast
Next 1 day
+0.2%
Next 1 week
+0.3%
Next 1 month
+1.0%
Seasonality
No real seasonal tilt
Next 30 days (to Nov 29): +0.2% median, 50% of the last 34 years finished up.
20-year seasonality chart →
Mean reversion
Deeply overbought — RSI(2) at 91
RSI(2) under 15 is oversold (this name has historically bounced); over 85 is overbought. Its dip-buy edge in history is -0.05%/day.
Mean-reversion stats →
1-month breakdown — Market · β 0.49 +1.4% · Seasonal tilt -0.4%
$139.4B market cap (#93 US) $661M/day volume 29% volatility +28% 1-year -4% from ATH
52-week range · 87% of the way up · -4% from the high
$403.16$560.25

Not investment advice.