IONS

Ionis Pharmaceuticals, Inc.
44.90 +2.14% 2026-10-28

Last 90d 1 insider buy worth $1.1M · 1 insider sale

52-week range
42.08 86.74
1-month-2.2%
3-month-15.7%
1-year-38.5%
3-year-1.9%
5-year+47.1%
vs 50-day-9.6%
vs 200-day-33.1%
Volatility43%
Beta0.51
$ vol/day$120M
ATH86.74
From ATH-48.2%
Next report2026-11-04
WhoEntryMove What they saidWhen
TRACKER - Cathie Wood long — -0.5% ARK bought 29,587 shares of ABNB for ARKW on 21 September 2026: 0.26% of that fund — roughly $4.9m at that day’s close.… Mon, 21 Sep
TRACKER - Cathie Wood long 51.44 -12.7% ARK bought 166,585 shares of IONS for ARKG on 14 September 2026: 0.49% of that fund — roughly $8.6m at that day’s… Mon, 14 Sep
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

WhenPeople SizeValuePrice
10d sell 2 $61,389 43.77
3mo buy 1 $1,058,700 52.30
4mo sched 3 $2,638,777 67.22
4mo sched 1 $910,416 82.60
4mo sched 3 $2,804,522 80.22
4mo sched 2 $7,664,949 80.72
4mo sched 2 $5,054,202 73.13
5mo sched 1 $605,360 73.07
5mo sched 1 $356,011 74.62
6mo sched 1 $5,801,037 76.36
6mo sched 1 $743,216 75.89
6mo sched 1 $116,731 75.78
6mo sell 3 $860,450 75.64
6mo sched 1 $381,367 75.64
7mo sched 2 $2,144,824 74.24
7mo sched 1 $412,478 71.91
7mo sched 1 $16,313,548 71.61
8mo sched 3 $15,705,211 75.27
8mo sched 6 $15,002,613 76.66
8mo sched 2 $1,692,527 81.17
9mo sched 1 $2,524,800 84.19
9mo sched 1 $7,056,340 84.25
9mo sell 8 $8,775,313 82.62
9mo sched 1 $323,489 80.66
9mo sell 11 $9,423,208 76.09
10mo sched 1 $3,760,577 81.27
10mo sched 1 $1,856,325 79.77
11mo sched 1 $2,262,920 82.03
11mo sched 2 $2,317,427 82.31
11mo sell 1 $3,173,720 73.95
12mo sched 2 $3,357,283 73.68
12mo sched 3 $10,103,770 73.60
1.0y sell 1 $3,902 73.25
1.0y sched 3 $2,613,324 73.25
1.1y sched 4 $1,553,093 70.73
1.1y sched 4 $8,291,436 67.19
1.1y sched 3 $8,662,282 65.59
1.1y sched 1 $109,786 61.11
1.1y sched 2 $2,098,572 63.50
1.1y sched 2 $373,100 62.85
1.2y sell 2 $13,256,475 59.80
1.2y sched 10 $19,691,979 59.80
1.2y sched 1 $60,690 42.14
1.2y sched 1 $439,800 42.61
1.2y sched 1 $209,654 41.31
1.2y sched 1 $428,600 41.77
1.2y sched 1 $408,697 43.02
1.2y sched 1 $109,440 42.84
1.3y sched 1 $48,418 42.30
1.5y buy 1 $477,900 32.61
1.5y sell 3 $216,381 28.40
1.6y sched 1 $4,525 33.26
1.7y sched 1 $39,046 32.12
1.7y sched 2 $1,424,318 32.99
1.7y sell 7 $705,371 31.73
1.8y sell 10 $2,989,350 32.17
1.8y buy 1 $181,075 36.24
2.0y sched 3 $808,961 37.28
2.0y sell 1 $2,030 38.88
2.2y sell 8 $3,067,767 47.20
2.2y sched 1 $32,159 47.42
2.2y sched 1 $116,640 46.97
2.3y sched 2 $681,021 48.69
2.4y sched 1 $644,640 40.58
2.5y sched 1 $256,283 41.49
2.5y sell 2 $204,352 41.18
2.7y sched 1 $17,218 45.09
2.7y sell 7 $1,760,910 49.90
2.7y sched 1 $654,707 49.90
2.8y sched 2 $452,036 51.45
2.8y sell 10 $4,358,355 50.73
2.8y sched 1 $428,000 50.69
2.8y sched 1 $1,360,149 52.80
2.8y sched 3 $8,296,299 50.11
2.9y sched 3 $2,827,445 50.64
2.9y sched 3 $2,837,398 50.04
3.0y sched 1 $100,000 49.10
3.0y sell 1 $2,493 47.21
3.0y sched 1 $173,420 47.78
3.1y sched 1 $207,390 46.11
3.1y sched 2 $541,560 46.62
3.2y sched 1 $26,970 40.02
3.3y sell 1 $149,310 41.97
3.3y sched 1 $787,962 41.79
3.4y sched 2 $261,583 41.87
3.5y sell 3 $260,391 36.56
3.7y sell 8 $1,508,006 40.47
3.7y sell 1 $356,085 40.45
3.8y sell 9 $2,785,892 40.19
3.8y sell 1 $80,000 39.70
4.1y sell 1 $20,493 47.51
4.2y sell 1 $45 44.52
4.3y sell 1 $50,977 39.47
4.5y sell 1 $16,689 41.44
4.5y sell 1 $272,088 41.05
4.6y sell 1 $13,309 38.66
5.3y sell 1 $152,990 35.87
5.3y sell 1 $566,100 38.38
5.4y sell 1 $549,500 37.22
5.7y sell 1 $12,810 54.50
5.8y sell 1 $1,805,945 60.69
5.8y sell 1 $338,074 60.55
5.8y sell 1 $4,609,317 62.84
5.8y sell 1 $8,390 61.95
5.8y sell 1 $10,918 56.17
2026AprJulOct

bought sold · bigger dot, bigger trade · follows the chart’s range

DGDaniel Goldman 1S 3.7y DSDonna Shalala 1B1S 7.4y TMThomas MacArthur 4B1S 10.0y SWSheldon Whitehouse 1S 10.8y

4 members · 5 buys / 4 sells · $37K–$205K disclosed · latest filing Apr 17, 2023 · full tracker ›

WhenMemberSize AmountPrice then
3.7y sell DG Daniel Goldman $1K–$15K 36.25
7.4y sell DS Donna Shalala $1K–$15K 63.84
7.5y buy DS Donna Shalala $1K–$15K 68.65
10.0y buy TM Thomas MacArthur $1K–$15K 27.00
10.0y buy TM Thomas MacArthur $15K–$50K 27.00
10.7y buy TM Thomas MacArthur $1K–$15K 35.13
10.7y buy TM Thomas MacArthur $1K–$15K 35.74
10.7y sell TM Thomas MacArthur $15K–$50K 35.61
10.8y sell SW Sheldon Whitehouse $1K–$15K 42.83

Next report 2026-11-04 (Wednesday, before open, in 6 days) · EPS estimate -0.93. It has finished the next session higher 53% of the time, average move 4.2%.

Day-after move, last 12 reports, oldest left.

ReportedEst.Actual SurpriseGapDay 1Day 5
2026-07-29 beat -0.88 -0.42 +51.7% -0.4% -2.3% -2.0%
2026-04-29 beat -0.77 -0.30 +60.9% +0.4% +4.2% +7.1%
2026-02-25 beat -1.22 -1.15 +5.6% -4.3% -5.3% -7.0%
2025-10-29 beat -1.05 -0.61 +41.8% -1.6% -2.3% +1.5%
2025-07-30 beat 0.16 0.85 +415.1% +8.4% +4.6% -1.9%
2025-04-30 beat -1.03 -0.92 +10.4% +6.6% +3.0% +10.9%
2025-02-19 beat -0.84 -0.43 +49.0% +8.0% -0.4% -0.6%
2024-11-06 beat -0.98 -0.72 +26.1% +3.0% +0.6% -2.6%
2024-08-01 beat -0.76 -0.24 +68.6% +0.8% +3.8% -3.9%
2024-05-07 beat -0.81 -0.77 +5.4% -3.1% -3.2% -9.5%
2024-02-21 beat -0.75 0.12 +115.8% +3.5% -1.8% +4.9%
2023-11-02 beat -0.89 -0.85 +4.8% +1.7% -3.4% +4.5%
2023-08-09 beat -0.70 -0.41 +42.5% +4.0% +1.1% +0.0%
2023-05-03 beat -0.76 -0.68 +10.4% +1.9% -2.2% +0.9%
2023-02-22 miss -0.86 -1.18 -37.5% +0.2% -3.7% -6.0%
2022-11-09 beat -0.53 -0.16 +69.7% +0.7% +1.9% +1.0%
2022-08-09 miss -0.47 -0.56 -20.1% -1.2% -3.2% -3.0%
2022-05-04 beat -0.52 -0.27 +47.1% +0.6% +2.8% -14.2%
2022-02-24 beat 0.31 1.55 +393.5% -3.0% +5.7% +8.2%
2021-11-03 miss -0.32 -0.34 -5.3% -0.2% +2.4% +1.0%
2021-08-04 beat -0.32 -0.26 +19.0% -0.6% +0.0% +1.1%
2021-05-05 miss -0.25 -0.32 -25.6% +0.2% -5.0% -11.1%
2021-02-24 beat 0.30 0.44 +48.8% +0.9% +0.3% -5.8%
2020-11-04 miss -0.16 -0.22 -37.5% -0.4% +1.3% +4.7%
2020-08-05 beat -0.28 -0.23 +17.9% +1.0% -3.0% -10.6%
2020-05-06 miss -0.11 -0.35 -204.3% -3.2% -2.1% -5.7%
2020-02-26 beat 1.03 1.33 +29.2% +3.0% +1.3% -1.3%
2019-11-06 beat -0.32 0.18 +155.9% +3.1% +2.2% +6.0%
2019-08-07 beat -0.20 -0.01 +95.0% +3.0% +5.6% +4.5%
2019-05-09 miss 0.78 0.62 -20.5% -0.9% -1.9% -1.3%
2019-02-27 beat — 0.20 +19707.8% +1.5% +15.1% +12.3%
2018-11-06 beat -0.17 -0.03 +82.5% +0.9% +4.1% +0.4%
2018-08-07 miss -0.19 -0.29 -56.4% -1.5% +1.3% +16.9%
2018-05-04 beat -0.15 -0.01 +93.5% +1.4% +6.6% +11.3%
2018-02-27 beat -0.04 0.02 +150.0% -2.7% +0.2% +0.5%
2017-11-07 beat -0.08 — +100.0% -4.1% -3.6% -1.3%
2017-08-08 miss -0.06 -0.09 -57.8% -1.6% -8.1% -11.5%
2017-05-09 beat -0.31 0.03 +109.5% +5.3% +3.3% -0.8%
2017-02-28 beat -0.11 0.24 +310.1% +4.4% +6.1% -0.8%
2016-11-09 beat 0.04 0.06 +38.9% +4.5% +22.0% +44.9%
2016-08-09 beat -0.52 -0.47 +9.6% +2.1% +1.2% -5.4%
2016-05-04 beat -0.54 -0.52 +3.7% +0.3% -7.8% -13.8%
2016-02-25 miss -0.54 -0.59 -8.4% -0.4% -4.4% +9.3%
2015-11-09 beat -0.33 -0.30 +8.3% -3.4% +12.4% +7.9%
2015-08-04 beat 0.29 0.29 +1.2% +0.4% +2.5% -6.4%
2015-05-05 beat -0.20 -0.14 +31.2% +4.1% -2.2% +3.8%
2015-02-27 beat 0.04 0.16 +325.2% +0.7% +1.8% +4.6%
2014-11-07 miss -0.20 -0.23 -12.2% -2.8% -1.5% +8.3%
2014-08-04 beat -0.11 -0.10 +11.1% +0.7% +3.4% +14.4%
2014-05-06 beat -0.28 -0.27 +4.4% -2.3% -3.7% -2.0%
2014-02-28 miss -0.18 -0.21 -13.5% +1.2% -9.5% -9.1%
2013-11-05 beat -0.30 -0.21 +29.7% +1.1% -2.8% -2.8%
2013-08-06 beat -0.25 -0.10 +60.8% -0.1% -3.1% -7.5%
2013-05-07 miss -0.02 -0.03 -68.8% -2.1% -10.2% -5.6%
2013-02-28 beat -0.19 -0.03 +83.9% +0.0% +3.3% +24.2%
2012-11-06 miss -0.29 -0.37 -28.7% -3.0% -7.2% -0.9%
2012-08-06 beat -0.08 -0.01 +87.7% +0.2% +9.2% +8.4%
2012-05-08 beat -0.28 -0.24 +14.9% -0.4% +2.6% +13.3%
2012-02-29 miss -0.13 -0.20 -56.2% +2.2% +5.8% -3.3%
2011-11-07 miss -0.20 -0.27 -32.0% -8.3% -9.1% -15.0%
Model view — historical tendencies for the days ahead, not a forecast
Next 1 day
-0.1%
Next 1 week
+1.1%
Next 1 month
+1.6%
Seasonality
Bullish window historically
Next 30 days (to Nov 28): +5.1% median, 65% of the last 34 years finished up.
20-year seasonality chart →
Mean reversion
Overbought — RSI(2) at 88
RSI(2) under 15 is oversold (this name has historically bounced); over 85 is overbought. Its dip-buy edge in history is -0.12%/day.
Mean-reversion stats →
1-month breakdown — Market · β 0.51 +1.3% · Seasonal tilt +0.3%
$120M/day volume 43% volatility -38% 1-year -48% from ATH
52-week range · 6% of the way up · -48% from the high
$42.08$86.74

Not investment advice.